Symptoms of extramedullary plasmacytoma

summary

Cancer is a disease that everyone is afraid of. It is undoubtedly a disaster to get this disease. Cancer can occur in almost all parts of the body. If cancer occurs in plasma cells, it becomes plasma cell tumor. Clinically, the disease is defined as the proliferation of malignant plasma cells outside the bone marrow. The symptoms of extramedullary plasmacytoma, let me tell you.

Symptoms of extramedullary plasmacytoma

Only 10% - 20% of the patients with solitary plasmacytoma had increased levels of monoclonal immunoglobulin or light chain in blood and urine. Most of the patients had no increased levels of monoclonal immunoglobulin or its polypeptide chain subunit (light chain), anemia, hypercalcemia, hyperviscosity syndrome, renal dysfunction and other symptoms.

More than 80% of the cases occurred in the head and neck, especially in the upper respiratory tract. The common parts included nasal cavity, paranasal sinus, nasopharynx, tonsil and so on. The clinical symptoms were nasal obstruction, epistaxis, hoarseness, hemoptysis, tears, facial swelling, decreased sense of smell, dyspnea and so on, especially nasal obstruction and epistaxis.

No matter where it occurs, plasmacytomas are space occupying lesions. The main signs of nasal cavity are polypoid hyperplasia or submucosal diffuse thickening, dark red or grayish yellow, smooth surface and medium texture. It can also occur in thyroid, lung, digestive tract, liver, spleen, pancreas, testis and skin, but it is rare.

matters needing attention

The disease is a serious malignant disease, so timely detection of the disease and active treatment is very important, and the clinical symptoms are the best basis for patients or doctors to judge the disease. Therefore, it is very helpful for the early treatment and prognosis of the disease to remember the clinical manifestations of the disease and clearly distinguish the two types.