What medicine does mania take

summary

In life, many people will collapse their psychological endurance due to the heavy pressure of life, and eventually manic disorder will appear. Let's talk about the drugs suitable for manic people.

What medicine does mania take

Drug 1: carbamazepine. ① mechanism of action: it acts on the diencephalon and limbic region, and the limbic system is the location of many mental diseases, which is the basis of CBZ in the treatment of affective disorders. (2) clinical application: it is effective in the treatment of various types of mania, and the curative effect is no less than that of lithium salt, especially in accelerating circulation. It is also effective for those who are ineffective in the treatment of lithium salt, so it can be used as the first choice drug for this type of emotional disorder.

Drug 2: sodium valproate. ① the mechanism of action is not very clear, which may be related to the increase of GABA content in brain. Adverse reactions: common gastrointestinal symptoms, such as anorexia, nausea, vomiting, dyspepsia, etc. A few patients had transient elevation of transaminase and mild tremor, hair loss, severe liver necrosis and acute pancreatitis.

Drug 3: lithium salt. ① pharmacological action: mainly related to lithium ion. Sleep and electrophysiology: it can prolong the time of slow wave sleep, prolong the latency of rapid eye movement, and shorten the period of rapid eye movement sleep. Cardiovascular system: often cause non-specific changes in ECG, T wave flattening or inversion. Endocrine and metabolism: it can inhibit the production, release and utilization of thyroxine. Urinary system: with the treatment dose of lithium, glomerular filtration function is mostly in the normal range, but renal tubular reabsorption function is often affected, clinical manifestations are polyuria, thirst symptoms, a few diabetes insipidus symptoms. (2) mechanism of action: the anti manic mechanism of lithium has not been elucidated, and the research mainly focuses on electrolytes, camp and central neurotransmitters. This is the most commonly used medicine, and the treatment effect is very good, the harm to the body is also very small.

matters needing attention

When the condition of manic patients is improved, it is better to let them contact social life as soon as possible, which helps to improve the patients' ability to adapt to the environment and help them return to normal life. People with manic disorder should not eat stimulating food in life, and should often participate in group activities.