Does child 5 years old have hemolytic disease what symptom

summary

Children 5 years old, there is no hemolytic disease, many people do not know, and most people do not know the symptoms of hemolytic disease. Hemolytic disease of the newborn refers to the blood group antibody produced in the mother's body that does not match the fetal blood group antigen due to the blood group incompatibility between the mother and the child. This kind of antibody enters into the fetal body through the placenta, causing homologous immune hemolysis. The blood group incompatibility between Rh blood group system and ABO blood group system is common. Other causes of hemolysis in the neonatal period are the defects of red blood cell enzyme or red blood cell membrane, which have a special name. Hemolysis with incompatible blood group is called hemolytic disease of the newborn. Let's share some experience.

Does child 5 years old have hemolytic disease what symptom

First: jaundice, neonatal hemolytic disease in children with jaundice early, Rh blood group incompatibility of hemolysis, most of the skin within 24 hours after birth appear obvious yellow, and rapid aggravation. In ABO incompatible hemolysis, 40% jaundice occurred within 24 hours after birth, 50% within 24-48 hours, and 10% after 48 hours. In addition to neonatal jaundice, hemolytic disease of the newborn is characterized by rapid rise of serum bilirubin level in a short time.

Second: anemia, in the neonatal jaundice appear and jaundice subsided, there may be varying degrees of anemia. It is mainly due to the destruction of a large number of red blood cells when hemolysis occurs. RH hemolysis may be accompanied by severe anemia, hepatosplenomegaly, and heart failure in severe cases. About 1 / 3 of ABO hemolysis appeared anemia. (3) Fetal edema was more common in severe RH hemolysis, manifested as systemic edema, pallor, skin ecchymosis, pleural effusion, ascites, heart failure and respiratory distress at birth. Serious cases can be life-threatening.

Third: nuclear jaundice, severe hyperbilirubinemia can lead to acute bilirubin encephalopathy, and then the formation of nuclear jaundice. The clinical manifestations included hand and foot movement, mental and motor development disorders, hearing impairment and enamel dysplasia.

matters needing attention

At present, it is limited to RHD antigen. A dose of RH immunoglobulin (rhdigg) was given intramuscularly within 72 hours after delivery to prevent RH hemolysis in the next fetus.