How fast does poorly differentiated cancer metastasize?

summary

Poorly differentiated adenocarcinoma is a kind of adenocarcinoma. Poorly differentiated adenocarcinoma: compared with well differentiated adenocarcinoma and moderately differentiated adenocarcinoma, the degree of differentiation of cancer cells is lower, similar to the immature form of the source tissue, such as poorly differentiated adenocarcinoma, glandular duct and acinar structure basically disappeared. Generally speaking, well differentiated adenocarcinoma has low malignancy and good prognosis. Poorly differentiated adenocarcinoma has high malignancy and poor prognosis. Undifferentiated adenocarcinoma has high malignancy and the worst prognosis.

How fast does poorly differentiated cancer metastasize?

The differentiation of tumor cells is very poor, and they are often diffusely arranged without aggregation tendency. If they can be identified as epithelial cells, they cannot be identified as squamous epithelium or glandular epithelium, they are called undifferentiated carcinoma. Similarly, tumors derived from undifferentiated mesenchymal tissue are called undifferentiated sarcomas. The lower the degree of differentiation of tumor cells, the higher the degree of malignancy, the faster the development, the earlier the metastasis, and the more sensitive to chemoradiotherapy.

Surgical resection is the main treatment for early stage of poorly differentiated adenocarcinoma. Patients with poorly differentiated adenocarcinoma whose clinical examination shows no obvious signs of metastasis, no serious organic lesions in important organs, estimated nutritional status and immune function can tolerate surgery should be explored by laparotomy. After the operation of early poorly differentiated adenocarcinoma, radiotherapy and chemotherapy, traditional Chinese medicine and immunotherapy can be used to prevent recurrence according to whether the operation is complete or not and the patient's tolerance.

The cells of a tissue go through various stages of differentiation from embryo to maturity. Generally speaking, the more primitive the cells are, the greater the potential of differentiation is, and the more complex the components of the tumor are. For example, the primordial germ cells have the ability to differentiate into various tissues, and the components of teratoma are very complex. Single component tumors have different morphological characteristics because of different levels of cell differentiation. According to different levels of cell differentiation, pathologists often divide some malignant tumors into well differentiated, moderately differentiated and undifferentiated.

matters needing attention

Biotherapy: biotechnology is a new tumor treatment mode with significant curative effect. It is to culture and expand the immune cells collected from patients in vitro, and then transfuse them back to patients to stimulate and enhance the body's autoimmune function, so as to achieve the purpose of tumor treatment.