Symptoms of metastasis of gastric cancer to bone

summary

Bone is the most common site of late metastasis of gastric cancer. Although bone metastasis will not cause death, it will bring great inconvenience to the life of patients due to bone pain. With the deterioration of the disease, serious symptoms of hemiplegia will appear. What are the symptoms of bone metastasis of gastric cancer?

Symptoms of metastasis of gastric cancer to bone

The typical symptoms of bone metastasis of gastric cancer are progressive local bone pain, percussion pain, anemia, fever and bleeding. A few patients may have local mass or complicated with pathological fracture, and some patients may have hypercalcemia. The typical X-ray manifestations were osteolytic destruction of bone. Radionuclide scan, CT or MRI scan could make a definite diagnosis.

Most of the bone metastases occurred in the trunk bone (the spine is the most common), followed by the femur and proximal humerus. It is rare to occur in the distal part of the knee and elbow. The characteristics of these bones are that the nutrient artery is the terminal artery, the vein is in the form of venous sinus, there is no venous valve, the vascular bed area is large and there is no medullary cavity, and there are many cancellous bones, so that the cancer cells are easy to be intercepted and propagated. In addition, multiple bone metastases are common in the whole body, and single bone metastasis is rare.

Radiotherapy is the first consideration in the treatment of local bone metastasis of gastric cancer. Radionuclide therapy is also a treatment method, but radionuclide therapy is mainly a kind of analgesic treatment, which can not control the tumor. It is suitable for patients with multi site bone pain caused by multiple small focal bone metastases but difficult to carry out radiotherapy.

matters needing attention

The treatment of bone metastasis of gastric cancer focuses on early detection and early treatment, which usually can obtain better therapeutic effect and greatly affect the survival time of bone metastasis of gastric cancer. Otherwise, it is difficult to effectively control multiple metastases in the later stage.