How does hyperuricemia get

Update Date: 2023-03-22 Source: Network

summary

Now there are many elderly people suffering from hyperuricemia, which has a great impact on the health of the elderly. Let me share with you how hyperuricemia comes from?

How does hyperuricemia get

First, excessive intake of exogenous purine: the high content of uric acid is directly proportional to the purine content in food. 50% of the RNA and 25% of the DNA in the food should be excreted in the form of uric acid in the urine purine composition. Strict restriction of purine intake can reduce the serum uric acid content to 60 μ mol / L (1.0 mg / dl) and the urine uric acid secretion to 1.2 mmol / D (200 mg / D).

Secondly, endogenous purine production is too much: endogenous purine metabolic disorder is more important than exogenous factors. The de novo synthesis of purine from noncyclic to cyclic goes through 11 steps, in which the abnormal number of enzymes will lead to excessive purine synthesis.

Third, the metabolic disorder of purine substances in the body leads to the reduction of uric acid excretion. 90% of patients with persistent high uric acid have abnormal renal function in handling uric acid.

matters needing attention

Hyperuricemia patients in daily life must pay attention to do more aerobic exercise, remember not to do too intense exercise, in order to avoid joint fatigue. It's best to choose aerobic exercise such as swimming, Taijiquan and table tennis to reduce weight. Drink plenty of boiled water or light tea, and the daily urine output should be controlled at about 2000ml, which is the best. Can use diuretic acid tea and job's tears porridge to reduce uric acid, drink less hot drinks, etc.