Why can kidney disease creatinine be high

summary

Kidney disease has always been a kind of refractory disease, which brings great pain and suffering to patients and their families. Kidney disease patients in the hospital examination, renal function examination is inevitable, in which serum creatinine will be significantly increased, what is serum creatinine? Why can kidney disease have blood creatinine to rise?

Why can kidney disease creatinine be high

Experts said that the diagnosis and treatment of kidney disease will pay attention to the change of serum creatinine to a great extent, and the decrease or increase of serum creatinine is also a standard of treatment effect. At the same time, the change of creatinine value often indicates that the body has pathological changes, especially when the kidney is damaged, the change of creatinine value is particularly obvious.

Our popular saying of serum creatinine is actually endogenous creatinine in clinic. Endogenous creatinine is a metabolite of human muscle. In muscle, creatinine is slowly formed by irreversible dehydration of creatine, which is then released into the blood and excreted in the urine. Therefore, it is generally believed that the amount of serum creatinine has a certain relationship with the total amount of individual muscle, and creatinine is not easily affected by diet. Creatinine is a small molecule substance in the body, which can be completely filtered through the renal bulb, but it is rarely reabsorbed in the renal tubules, that is to say, almost all of the creatinine produced daily in the human body is excreted with urine.

A simple increase in serum creatinine does not mean that there must be kidney disease. Some systemic diseases, such as acromegaly, gigantism, diabetes and infection, can cause a rise in serum creatinine. In addition, when eating meat, exercising and taking drugs such as vitamin C, levodopa and methyldobba, there may also be a rise in serum creatinine.

matters needing attention

Many related factors can cause high creatinine, so we must pay more attention to our living habits in our daily life, find the disease in time, and go to the regular hospital for treatment in time. In the process of treatment, we should cooperate with the doctor's advice, and we should avoid some irritating food in our daily diet.