What is the cause of endometrial thickening?

summary

I believe that this disease should not be unknown. In recent years, the number of women suffering from endometrial diseases is increasing. However, many people do not pay attention to the prevention and early treatment of this disease at all, which will delay the best treatment opportunity and eventually affect their fertility. So why does the female endometrium thicken? Some experts have pointed out that the main reason for endometrial thickening is the continuous stimulation of estrogen, which is related to the endometrium. This performance is a large number of irregular uterine bleeding, bleeding after a long period of amenorrhea, patients with prolonged menstruation.

What is the cause of endometrial thickening?

First, one of the reasons for endometrial thickening is that the lesion uterus is slightly larger and the endometrium is obvious. After treatment, it sometimes appears as diffuse polypoid. The curettage material is large and can be mixed with red smooth polypoid tissue. Microscopically, the lesion was diffuse, involving the functional layer of the intima. The stroma and glands proliferated at the same time, but did not show gland crowding.

Second: the second reason is the complex hyperplasia of endometrium. The etiology of complex hyperplasia is similar to that of simple hyperplasia. However, because the lesion is focal, it may be related to the distribution of hormone receptors in the tissue. Curettage can be more or less, often have normal atrophy or other types of endometrial hyperplasia.

Third: three reasons. Endocrine functional tumors are one of the reasons for endometrial thickening. Endocrine functional tumors are rare tumors, accounting for about 7.5% of tumors. The gonadotropic function of pituitary gland is abnormal. Ovarian granulosa cell tumor is also a tumor that continuously secretes estrogen.

matters needing attention

In addition, obesity is also one of the causes of endometrial thickening. Androstenedione secreted by the adrenal gland of obese women is converted into estrone by aromatase in the ovary tissue. The more adipose tissue, the stronger the conversion ability, and the higher the level of estrone in the plasma, which will cause persistent estrogen effect.