What causes dwarfism

summary

Dwarfism is mainly due to genetic disorders, resulting in the body and bone development is not proportional to intelligence development is usually normal. Now let's see what causes dwarfism.

What causes dwarfism

First of all: the disease can be divided into primary and secondary two categories, the etiology of primary is unknown, mostly caused by congenital hypoplasia or genetic diseases, may be autosomal recessive inheritance, familial, mainly with single growth hormone deficiency, boys are more common than girls, the ratio of men and women is about 2-4:10.

Secondly, the secondary can be secondary to the hypothalamus pituitary diseases, such as tumor, infection, craniocerebral trauma, surgery or radiotherapy and other factors, which directly damage the pituitary, or damage the hypothalamus, or interrupt the pituitary portal system. Hypothalamus pituitary tumor is an important cause of secondary pituitary dwarfism.

Finally: the pituitary changes of primary pituitary dwarfism include: congenital hypophysis absence, congenital hypophysis hypoplasia with eosinophil deficiency or decrease. Pituitary atrophy, fibrosis or cystic change with calcification. In addition to pituitary gland changes, gonad, thyroid gland and adrenal cortex atrophy in varying degrees, visceral and bone growth stagnation in infancy. Secondary tumors are more common in the hypothalamus pituitary region, especially craniopharyngioma. Chromophobe cell tumor of pituitary is less common in children, but it can also cause dwarfism early.

matters needing attention

Many patients with dwarfism also have other diseases, such as diarrhea or some trauma and severe vomiting. Some patients have special conditions and need regular physical examination, and pay attention to supplement calcium.