What causes trisomy 18

summary

It's not very difficult to understand trisomy 18. As we all know, women need to do a lot of pregnancy tests during pregnancy. Everyone's understanding is different. Every item is very important. We can see the development of the fetus. Noninvasive DNA is one of the items of prenatal examination during pregnancy. So, what's the reason for the high level of trisomy 18?

What causes trisomy 18

First: in prenatal screening report, 1 / 1000 ≤ Down's syndrome risk rate test value ≤ 1 / 270, 1 / 1000 ≤ 18 trisomy syndrome risk rate test value ≤ 1 / 350, 1 / 1000 ≤ 13 trisomy syndrome risk rate test value ≤ 1 / 350, namely serological screening, imaging examination showed that common chromosome aneuploidy close to high risk.

Second: limited by the level of technological development, at present, the main three common chromosomal diseases in domestic non-invasive DNA screening are T21 chromosomal abnormalities (Down's syndrome), T18 chromosomal abnormalities (Edwards syndrome) and T13 chromosomal abnormalities (PatoW's syndrome).

Third: in the larger gestational age (20 weeks + 6 days), and just within the time of noninvasive DNA prenatal testing, we have missed the best time of serological screening or prenatal diagnosis, but there are special requirements for reducing the risk of three major chromosomal diseases.

matters needing attention

In addition, if blood collection also involves routine blood test items such as liver function, blood glucose and lipid, it is recommended to discuss with the doctor whether it is necessary to conduct non-invasive DNA prenatal testing separately or at the same time.