Paraquat poisoning symptoms?

summary

One of my neighbors drank paraquat today. Paraquat is a common herbicide, but it has strong toxicity. In addition to the weeding work will come into contact with, usually in ordinary days, if paraquat storage is not appropriate, greedy roadside unclean wild fruit, etc., may also make people poisoned. If the patient swallows a small dose and shows mild poisoning, it is more likely to be cured. If the patient shows severe poisoning within one or two days, there is little hope for follow-up rescue. So paraquat poisoning symptoms? Let's talk about it

Paraquat poisoning symptoms?

Paraquat is absorbed quickly after oral administration. It mainly accumulates in the lung and muscle, and its secretion is slow. Therefore, the toxic effect can continue to exist. The lesion mainly occurs in the lung, which is called paraquat lung. Herbicides can attack peroxides, damage type I and type II alveolar epithelial cells, cause swelling, degeneration and necrosis, and inhibit the attack of pulmonary surfactant.

The pathological changes were proliferative bronchiolitis and alveolitis. The morphological changes of the lung depended on the survival time after ingestion. The patients who died within one week showed hyperemia, edema and lung weight addition, which was similar to oxygen poisoning. The patients who survived more than one week had organized alveolar exudates (including dropped alveolar epithelial debris, macrophages, red blood cells and hyaline membrane) and moistened monocytes.

Hemorrhage, proliferation of interstitial fibroblasts and thickening of alveolar interstitium result in extensive fibrosis, forming honeycomb lung and bronchiectasis. Paraquat poisoning can lead to renal tubular necrosis, damage of hepatic central lobular cells, necrosis, myocarditis, thickening of middle layer of pulmonary artery, necrosis of adrenal cortex, etc.

matters needing attention

The main thing is to pay attention to personal cleaning, rest and relaxation in ordinary days. It is good for your health to eat more fresh fruits, quit smoking and drink. The patients who are out of the risk of death after poisoning should make up for the water in time, or they can be infused with physiological saline. After healing, the diet should be clean and light, and reduce the influence of tobacco and alcohol, spicy diet on gastric mucosa.