Symptoms of retinitis pigmentosa

summary

Retinitis pigmentosa is a kind of hereditary retinopathy with progressive visual impairment. Typical fundus changes in the optic disc, thinning of small blood vessels, discovery of the equatorial portion of osteoid pigment, night blindness and decreased vision are the most important complaints. Symptoms of retinitis pigmentosa? Let's talk about it

Symptoms of retinitis pigmentosa

In the early stage of dark adaptation, the function of cone cells was normal, the function of rod cells decreased, the terminal threshold of rod cell curve increased, and the light color difference decreased. In the late stage, the function of rod cells was lost, and the threshold of cone cells was also increased, forming a high monophasic curve.

There were annular scotoma in the early visual field and central visual acuity, and the location was consistent with the equatorial lesions. After that, the annular dark spot gradually expands to the center and periphery to form a tubular field of vision. The central visual acuity was normal or nearly normal in the early stage, and gradually decreased with the development of the disease. Under general illumination, when the peripheral visual field was completely lost, the central visual field remained for 5 days °～ ten °， The patient was in the state of tube vision. Finally, the central vision gradually lost, and finally completely blind. In the natural course of RP, visual field loss was 4.6% per year.

No response to visual electrophysiological ERG, especially the disappearance of B wave, is a typical change of the disease, which often occurs earlier than the change of fundus. EOG LP / DT was significantly decreased or extinguished, even in the early stage, when the changes of visual field, dark adaptation and even ERG were not obvious. Therefore, EOG is more sensitive than ERG in the diagnosis of this disease.

matters needing attention

Patients with recessive inheritance should try to avoid marriage with the family history of the disease, let alone those who also have the disease. The risk of children with dominant inheritance is 100%. The type of vitamin A deficiency is effective.