Tetanus symptoms for seven days?

summary

Tetanus is a kind of specific infection that Clostridium tetanus invades human body through skin or mucosal wound, grows and reproduces in anoxic environment, produces toxin and causes muscle spasm. Tetanus toxin mainly invades the motor neurons in the nervous system. Therefore, the clinical features of this disease are closed teeth, paroxysmal spasm and tonic spasm. The main muscle groups affected include masseter muscle, dorsal spine muscle, abdominal muscle and limb muscle. Tetanus symptoms for seven days? Let's talk about it

Tetanus symptoms for seven days?

The main manifestations were de inhibition of the motor nervous system, including myotonia and muscle spasm. Generally, the first muscle group affected is masticatory muscle, followed by facial expression muscle, neck, back, abdomen and limbs muscle, and finally diaphragm muscle. The signs of myotonia are difficult to open mouth and close teeth, the abdominal muscles are as firm as plates, the neck is stiff and the head is tilted back. When the back and abdominal muscles contract at the same time, the trunk is twisted into a bow because of the strength of the back muscles, thus forming "diagonal arch reflexes" or "lateral arch reflexes".

Paroxysmal muscle spasm occurs on the basis of myotonia and persists during the spasmodic interval. The corresponding signs were frowning, mouth angle shrinking and grinning (hemifacial spasm); Laryngeal obstruction, dysphagia, cough (pharyngeal muscle spasm); Dyspnea, cyanosis, respiratory arrest (respiratory muscle and diaphragm spasm); Urinary retention (sphincter spasm *). Strong muscle spasm, can make muscle rupture, even fracture. The main causes of death were asphyxia, heart failure or pulmonary complications.

The above attacks can be induced by mild stimulation, such as light, sound, contact, drinking water, etc., and can also be spontaneous. In mild cases, muscle spasm occurred no more than 3 times a day; Severe patients have frequent attacks, which can occur once in a few minutes, even in a continuous state. The duration of each attack ranged from a few seconds to a few minutes.

matters needing attention

Application of antitoxin: the purpose is to neutralize the free toxin, so it is only effective in the early stage. If the toxin has been combined with nerve tissue, it is difficult to achieve effect. However, as the allergy rate of antitoxin is as high as 5% ～ 30%, intradermal allergy test should be done before using antitoxin. Tetanus human immunoglobulin in the early application of effective, generally only once.