Is cervical leukoplakia precancerous lesion?

summary

Leucoplasia of the cervix refers to a kind of gray opaque plaque like lesion in the cervix and vagina. Most scholars believe that the clinical naked eye white spots only show different degrees of epithelial hyperplasia. With the in-depth study of cervical precancerous lesions and early cancer and the wide application of colposcopy, the disease has gradually attracted attention. Let's talk about cervical leukoplakia is not precancerous lesions?

Is cervical leukoplakia precancerous lesion?

1. The etiology of cervical leukoplakia is not clear, which may be related to the following factors: 1) endocrine imbalance: the increase of estrogen content in the body, resulting in abnormal keratinization of cervical surface epithelium（ 2） Local stimulation: such as chronic cervicitis, vaginal Trichomonas, etc. Zhongshan Medical University has found 37 cases of cervical leukoplakia (5.2%) in 700 cases of cervical erosion biopsy pathological clinical analysis, which shows that the incidence of chronic cervicitis is significantly increased（ 3） Other factors: according to literature reports, cervical leukoplakia occasionally coexists with atypical hyperplasia, carcinoma in situ or early invasive carcinoma. It is considered that the occurrence of cervical leukoplakia may be related to the carcinogenic factors of cervical cancer.

2. Gross observation showed that there were white opaque patchy areas on the surface of the cervix, with different sizes and shapes. Generally, the lesions were small, with a diameter of less than 1cm. Single or multiple, individual cases of leukoplakia can go beyond the cervix to the vaginal vault. The surface is grayish white or only slightly brighter than the surrounding pink mucosa. Some of the edges are neat and the boundaries are clear, while others are irregular. It is easy to wipe off the surface of the white spots with cotton swabs, and the bottom is dotted with bleeding.

3. The following features can be seen under the microscope: (1) hyperkeratosis or incomplete keratosis on the surface of leukoplakia; ② Epithelial cells proliferated and hypertrophied, accompanied by thickening of spinous cell layer; ③ The granular cell layer was thickened and the epithelial foot was extended and widened; ④ There were round cells and lymphocytes in the subepithelial stroma. According to the characteristics of tissue morphology, cervical leukoplakia was divided into two grades. There were only 2-3 layers of keratosis or incomplete keratosis on the surface of cervical epithelium, and those with normal spinous cells and basal cell layer or benign hyperplasia were grade I leukoplakia; The dysplasia of epithelial cells under the keratotic layer was grade II leukoplakia.

matters needing attention

The diet of cervical leukoplakia should be adjusted according to the menstrual period. Patients with cervical leukoplakia should pay attention to eating less spices, less meat and more vegetables if they often come early or the cycle is too short; If menstruation is always late, it is better to eat less cold food and more tonic food, such as meat and grains. Especially, on the first and second day of menstruation, you should take more blood enriching food. It is better to eat ginger fried chicken liver or pig liver