What are the causes of high uric acid

summary

Grandfather Wang's leg has been suffering from gout recently. When it is serious, he can't even walk. He can only sit at home and have a rest. The doctor says that these phenomena are caused by high uric acid. Let me talk about the causes of high uric acid.

What are the causes of high uric acid

First, exogenous purine excess. Dietary intake of purine is the main source of exogenous purine, such as fish, seafood, beans, and wine. When these foods are ingested, it will directly increase the synthesis of uric acid in the body, resulting in high uric acid. Excessive endogenous purine synthesis. It refers to the high level of uric acid caused by the increase of purine synthesis. When the metabolism in the body is disordered, the synthesis of uric acid will change, and then the synthesis of uric acid will increase.

Second: genetic material. From the microscopic point of view, purine mainly comes from the cell nucleus, and the main component of genetic material in the nucleus is purine. When human erythrocytosis and myeloproliferative diseases appear, it is easy to lead to high uric acid, but this situation is very rare.

Third: the complication causes the uric acid to be high. Studies have shown that many diseases are related to high uric acid. When the body has pathological changes, it will have a certain impact on some functions of the body, which will cause metabolic disorders of uric acid, and then indirectly cause the occurrence of high uric acid.

matters needing attention

Hyperuricemia is caused by the excess of purine in the body. The causes of hyperuricemia and diet are quite important. In addition, some diseases cause the disorder of various functions of the body, which may also cause hyperuricemia.